"Maybe we were close to something he's planning. So he ran us off. Except...then why did he kill Gregson? We're gone, we're running. This is more than just a case."

She shakes her head slightly. Why was this so personal for Moriarty? He killed Irene, fine. He drove Sherlock away from London, drove him to addiction. But now? Now it's beyond just making Sherlock go away.